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For example, induction of the primitive streak, the structural harbinger of mesendoderm formation in the embryo, requires the activity of a number of secreted growth factors (reviewed in [5]).
A variety of pathways induced by HIF have already been reported to protect from the latter effect, for example induction of pyruvate dehydrogenase kinase inhibits the enzyme complex of pyruvate dehydrogenase and blocking the conversion of pyruvate to acetyl coenzyme A, the first step in the Krebs cycle [6] and enhances lactate production [7].
For example, induction of neurodegeneration mimicking Parkinson's disease requires days of treatments [ 41, 42].
This can possibly be due to the glucose-sensing mechanisms in yeast (for example, induction of hexose transporters) [ 27].
For example, induction of inflammation by bacterial and viral infections increases cancer risk (Ferreri et al, 2009).
For example, induction of autophagy is essential for steroid sensitization in childhood acute lymphoblastic leukemia cells, which requires necroptosis, a form of programmed necrosis.
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We examined the adjuvant activity of the TNF/CHP nanoparticles, for example, enhanced induction of antigen-specific antibodies in mice, particularly in the case of nasal administration.
For example, with induction of gram-negative sepsis, myocardial protective effects are demonstrable at 6 h [18,25], and the myocardial protective effects of LPS exposure were reported to appear after 12 to 24 h [12].
For example, high induction of the chemokines CCL1 and CCL18 is found in the lesional skin of patients with atopic dermatitis (Gombert et al., 2005; Pivarcsi et al., 2004).
For example, collaborative induction of inflammatory responses to the fungi Candida albicans and Pneumocystis carinii has been observed with TLR2 and Dectin-1 [25]–[27].
It is desirable to further test the regulation in other physio/pathological contexts, for example, the induction of Beclin 1 and autophagy during reperfusion phase after cardiac ischemia.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com