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For example, in a trial of 500 subjects, for a vaccine that has a 50% efficacy, misallocation of only 25 (5%) subjects has an estimated efficacy of 44% 95%% confidence interval (CI) of 41% 45%), and this is a relative error of ∼12% 955% CI of 10% 18%) from the true vaccine estimate (Figure 3a).
For example, in a trial of breastfeeding support groups, leaders interpreted the word "support" in different ways.
For example, in a trial showing a small difference between two treatment arms, approximately 50% of patients will have received treatment, which was, on average, 'inferior'inferior
For example, in a trial of pelvic floor muscle training for stress urinary incontinence, a 64% response rate was reported for the sham (placebo) intervention arm [ 46].
69 For example, in a trial by Kim and Lee, 114 frail older persons received energy protein supplementation over 12 weeks, which reduced functional decline in this population compared with placebo controls.
For example, in a trial designed to give 80% power, ICCs of 0.01, 0.10, and 0.25 would lead to reductions in power of 0.4, 4.3, and 12.1% respectively if centre was ignored in the analysis.
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For example, women in a trial of acupuncture for menopausal symptoms associated with tamoxifen hoped for particular outcomes as well as (or instead of) expecting them [ 38] as did women in a trial of acupuncture for polycystic ovary syndrome [ 39].
For example, in a murder trial, the blood on a blood-stained knife may be considered data relevant to the trial, but in a cookery competition it simply shows that basic hygiene standards have not been observed.
For example, in a signal trial featuring a picture of a teapot, a response would be coded as correct if the participant reported seeing a teapot and indicated its presence in the correct spatial location on the screen.
For example, in a human trial with equipoise, the prior probability of the null hypothesis is 50%, and a p = 0.05 means the probability of the null hypothesis is down to no lower than 13% [64] [66].
For example, in a modeled trial of 500 subjects, misallocation of CCL3L1-CCR5 genofype onlynly 25 (5%) subjects between placebo and vaccine arms results in a relative error of ∼12% from the true vaccine efficacy.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com