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Telomere length, for example, has been observed to be shortened (Vaziri et al., 2010), similarly sized, or even elongated compared to ESCs (Lapasset et al., 2011).
Reduced motor variability, for example, has been observed in subjects with chronic pain [ 39], and may be emblematic of a pre-existing motor dysfunction or of an inappropriate long-term compensation following an acute injury [ 40].
A particularly dramatic example has been observed in a subset of bone-derived cultured macrophages, where lysosomes form abundant, extended tubules that radiate from the cell center and, in some cases, form an interconnected web throughout the cytoplasm (Swanson et al., 1987a; Knapp and Swanson, 1990).
The most striking example has been observed in the great reed warbler, where a female:male map length ratio of 2.15 was initially observed (Hansson et al., 2005), although a subsequent study with more markers revised this down (female:male ratio=1.56; Åkesson et al., 2007).
A recent similar example has been observed in hepatocytes where the suppression of cell proliferation by C/EBPα is lost during oncogenesis by dephosphorylation of C/EBPα which leads to failure of C/EBPα to interact with cdk2 and E2F as well as sequestering retinoblastoma protein [ 39, 40].
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Migrating passerines, for example, have been observed at altitudes as great as 4,000 metres (14,000 feet).
Young chimps, for example, have been observed intently watching as their elders show them how to crack open nuts using rocks.
Natterjack toads, for example, have been observed on arable land, e.g. in cereal fields, where during the day they sit on the ground or bury themselves [11].
Tropical species, for example, have been observed to reproduce throughout the year [12], [13], [47].
Kinematic changes at the knee and hip, for example, have been observed post-fatigue for men and women performing single-leg stop jumps [ 33], landings [ 34– 36], maximal repeated jumps [ 37], and sidestep cutting manoeuvres [ 38].
In the journal Polar Biology, the researchers said that no previous examples had been observed in the region in at least 24 years.
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