For example, for trials with small sample sizes, a t test may have been used.
Examples for trial visits for chemotherapy regimen with eight cycles are given as Additional file 1 and Additional file 2. CoC is defined as primary endpoint and can be assessed objectively immediately after completion of treatment.
For example, for a trial with the primary outcome of myocardial infarction, stroke or cardiovascular death, a participant may experience a stroke and then die a cardiovascular death.
As participants' inconvenience and time contribution increases, increasing benefits are likely to be appropriate, for example for clinical trials (such as phase 2b and 3 vaccine/drug trials with prolonged follow up) and longer term observational studies.
And councils can make exceptions, for example for clinical trials, which tend to cost more than lab research.
For example, reports for trials that use combination of gemcitabine plus carboplatin, showed outcomes of progression-free survival of only 3.6 months reported for control arm (almost insignificant, and no cure).
(b,c ) Raster plot and peri-stimulus time histogram (PSTH) of two example cells for trials in which the longest stimulus interval (2.4 s) was presented.
Examples "For each trial we plotted the effect by the inverse of its standard error.
For example, for the simulated trial for insulin resistance, we created a hypothetical treatment that maintained the effects of insulin on liver, fat, and muscle at their normal levels.
