For example, expression of the non-coding, maternally expressed gene Meg3 has been shown to be lost in many kinds of primary human tumors and tumor cell lines.
For example, expression of ncRNA SprA was specifically inhibited by L. Although the genes have been categorized into three groups (i.e., universal, bi-specific, and unique), individual genes in the same group showed different expression levels.
For example, expression of PPARα-regulated mitochondrial Hmgcs2, the rate-limiting enzyme involved in the production of ketone bodies39,71, including β-hydroxybutyrate, a known endogenous HDAC inhibitor17,18, is decreased in mutant enteroids.
For example, expression of E-cadherin is used to describe a cell as being in an epithelial state whereas expression of N-cadherin, vimentin, and/or fibronectin 1 are used to describe the mesenchymal phenotype (see Figure 1).
For example, expression of scpA was decreased in a biofilm but elevated in a sarA mutant.
For example, expression of TGFβ1 is increased in stromal cells as they undergo decidualization [20], [21].
For example, expression of Sema3E in prostate cancers and metastatic melanoma inhibits adhesion and motility of cancer cells [38], [39].
For example, expression of full-length CFTR protein at the apical cell membrane was observed in cystic fibrosis patients [17].
For example, expression of the replication-related proteins encoded by CPMV RNA-1 is known to induce a massive proliferation of endoplasmic reticulum (ER -derived mER -derived0]–[12].
For example, expression of cyclin F and ERK1 were down-regulated ∼2 fold (∼0.5 fold of control), while cyclin A1 and KRAS were up-regulated ∼2 fold.
For example, expression of the transcription factors, SIX6, EGR2, PKNOX2, HOXD4, HOXD10, DLX5 and RAXL1, known to regulate developmental processes, are retained in AFiPSCs and FiPSCs.
