Then we give the main features of DIYABC and we provide two complete example analyses performed with this program to illustrate its possibilities.
Secondary analyses will include exploratory analyses among persons within subgroups defined post-randomization--for example, analyses among persons with greater versus lesser knowledge of LRT at baseline.
We will also perform exploratory analyses among persons within subgroups defined post-randomization--for example, analyses among persons with greater versus less knowledge of LKT at baseline.
The indicated formal representations and associated numerical procedures for the evaluation of PLOAS are illustrated with example analyses involving (i) only aleatory uncertainty, (ii) aleatory uncertainty and epistemic uncertainty, and (iii) mixtures of aleatory uncertainty and epistemic uncertainty.
Example analyses using data from landfill facilities with relatively low and high heat generation indicated thermal energy in the range of −48.4 to 72.4 MJ/m3 available for heat management.
As an example, analyses of simulations from scenario g with 1000 traits and 1000 individuals took about 4 hr to generate 12,000 posterior samples on a laptop computer with a 4-core 2.4-GHz Intel Core i7, while analyses of scenario a with 100 traits took ∼45 min. Parallel computing techniques may speed up analyses in cases of very large (e.g., 10,000+) numbers of traits.
Because of the possibility of de-anonymising single cases, data are only accessible in not-too-sparse strata, obviating all analyses that use individual case data, for example, regression analyses with simultaneous adjustments for more than one confounder, or even interactions between confounders.
Future studies could evaluate the underlying factors contributing to higher healthcare utilization rates as well as the factors underlying more favorable outcomes such as lower utilization rates (for example, regression analyses with ER visits and inpatient hospitalizations as outcome variables).
For example, individual-based analyses with thousands of markers can provide extremely accurate estimates of individual genetic variation.
The use of the numerical model is demonstrated with examples analysing the impact on heat exchanger effectiveness of a changed geometry (design analysis) and of varying air inlet conditions for a given geometry (operational analysis).
