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For example, alterations have been shown in Alzheimer's disease, Morbus Parkinson, major depressive disorder and attention deficit hyperactivity disorder [1 9].
For example, alterations in intracellular calcium levels can affect smooth muscle contraction downstream [54].
For example, alterations in A-type lamins in humans correlates with changes in heterochromatin organization [68], whereas, Drosophila nuclei lacking Lamin C showed no obvious changes in heterochromatin (Fig. 4 and 5).
For example, alterations in RSPO4 activity have been reported to cause anonychia in humans [22], whereas disruption of Rspo2 or Rspo3 in mice affects development of several different systems (skeletal, respiratory or placenta defects) [23].
For example, alterations in the ECM simultaneously induce changes in viscoelasticity of the cartilage.
For example, alterations of auditory feedback during speaking can affect motor control of articulatory movements (Houde & Jordan, 1998).
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For example, alteration of KCNMA1 function has been associated with several complex human disorders including cancer.
At ECL, for example, alteration of the recorded EPSC by inhibitory neurotransmitter is expected to reflect presynaptic changes (notwithstanding metabotropic modulation of postsynaptic glutamate receptors).
A limited number of studies have investigated alterations in the expression patterns of regulatory genes in developing tissues in vivo in response to immobilisation, showing for example alteration in FGF2 [37], IHH and COLX [22].
For example, alteration in TNFRSF10B transcript abundance may disrupt cell cycle control and induce the development of carcinogenesis.
For example, alteration in the relative abundance of various plasma lipoproteins such as low-density lipoprotein (LDL) and high-density lipoprotein (HDL) has been shown to be of primary importance in the development of the disease.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com