For example, if all cells are derived from initial progenitor cells, what directs differentiation towards glial cells versus adipocytes?
However, there were a few discrepancies as might be expected; for example, not all cells that fail to grow become immediately phloxin B positive, and the time to resume growth will also depend on the growth kinetics of mutant cells.
As a more specific example, not all cells in a solid tumor are exposed to the same microenvironmental cues: cells at the leading edge of a tumor receive more nutrients and oxygen, are more metabolically active, and are more likely to undergo active proliferation and invasion than those closer to the tumor core.
For example, all living cells use the same basic set of nucleotides and amino acids.
For example, all tested cell lines (e.g., B14, BRL-3A, and mHippoE-18) rapidly accumulated PAMAM-pyrrolidone dendrimer.
For example, not all cell surface components will posses sufficient antigenicity to elicit a strong antibody response in immunized animals and, even if tight binding antibodies are obtained, there may be algae in which the target antigen is produced in very low quantities or may produce target antigens that are buried or masked within the cell wall.
For example, all 6 MM cell lines and approximately 95% of 43 primary MM samples carried mutations in at least 1 adhesion molecule, RTK or RTK downstream-signaling effector that all cluster within the same signaling network, indicating that pathways belonging to this network are of importance in MM pathogenesis.
During larval development and in adults, CDC-42 localized to cortexes in all cells, for example, in the vulva and in the tail (Supplementary Figures S5A C).
Consistent with neutral drift dynamics, we observed CCO− populations located only in the lower portion of the crypt (a CCO− clone), ribbons disconnected from the crypt base (clone extinction), and examples of clone fixation where all cells become CCO−.
For example, cell migration involves cell detachment, adhesion and invasion, while invasion involves migration and adhesion.
