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Therapies designed to reinforce the circadian axis (for example, administration of melatonin or light) have been reported to alleviate the disturbed circadian rhythms and disrupted sleep.
For example, administration of a peptide sequence unique to tissue remodeling/fibrotic (M2) macrophages identified by subtractive phage biopanning and fused to the KLA proapoptotic peptide [286] decreased mortality in CT-26 tumor-bearing mice by inducing a decreased number of tumor-associated macrophages [287].
For example, administration of NT or NT analogue can stimulate DA-dependent behaviors, while NT antagonist can block the effect of NT analogue [19], [20].
For example, administration of cocaine or the presentation of drug-related cue can enhance evoked responses in the primary sensory cortex of experimental animals and humans [7], [8].
In quail embryos, for example, administration of genistein after three days of incubation leads to a decrease of copulatory behavior at puberty [63], but the possible effects during embryogenesis have not been assessed.
For example, administration of the PPARγ ligand rosiglitazone reduces foam cell formation and atherosclerosis in LDL-R knockout mice [23], and transplantation of PPARγ-deficient bone marrow into recipient LDL-R knockout mice enhanced atherosclerosis [24].
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In addition to these examples, administration of sodium bicarbonate to maintain a pH of 7.2 during controlled hypoventilation has been investigated in patients with status asthmaticus [ 44]; however, no studies have demonstrated any benefit associated with bicarbonate infusion.
In model systems of HD, for example subcutaneous administration of FGF2 increased neurogenesis [ 61] and overexpression of metallothioneins conferred neuroprotection against polyglutamine induced excitotoxicity [ 62].
During World War I, for example, the administration of Woodrow Wilson conducted a devastating campaign to squelch dissent.
In 2002, for example, the administration of Gov. George E. Pataki deemed one of Mr. Paladino's companies eligible for tax incentives under a program intended to encourage economic development.
For example, intranasal administration of OT appears to trigger caregiving behavior and to improve the recognition of emotional facial expressions.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com