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For example, a fusion of the X chromosome with an autosome has been described in D. robusta and relatives in the robusta species group [ 35, 36].
For example, a fusion of the X chromosome with an autosome will produce an expanded X chromosome while the remaining sister chromosome will become an additional sex chromosome.
There is evidence for this from animal models; for example, a fusion protein of osteoprotegerin which inhibits RANK-RANKL interactions can prevent bone erosion in TNF-transgenic mice [ 59].
For example, a fusion event between one damaged and one undamaged mitochondrion has the potential to dilute out damaged components in the former, thereby repairing the damaged organelle via the process of 'functional complementation' (Youle & van der Bliek, 2012).
For example, a fusion protein of full-length Pex3 and GFP, expressed under control of the PEX3 promoter in H. polymorpha pex19 cells, localizes to the cytosol (Otzen et al. 2004).
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A recently discovered example is a fusion between the genes echinoderm microtubule-associated protein like 4 (EML4) and anaplastic lymphoma kinase (ALK), generated by an inversion on the short arm of chromosome 2: inv(2)(p21p23).
The most infamous example of a fusion reaction is the hydrogen bomb, which sacrificed control and safety for the sake of violence and death.
It could be used, for example, as a fusion tag to study protein trafficking and localization under both aerobic and anaerobic environments.
The 1961 Tsar Bomba explosion was the largest nuclear detonation ever to take place on Earth, and is perhaps the most famous example of a fusion weapon ever created, with a yield far surpassing any other ever developed.
Figure 2 illustrates the MON2-MARS gene fusion as one example of a fusion transcript.
Inset shows a typical example of a fusion event reported by NPY-pHluorin.
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