Eastern European artists were still adept at copperplate engraving, for example, a difficult, labor-intensive skill hardly practiced in the West.
Using a smartphone app, with the idea of users being "secret agents" for the city, children can send immediate reports on their route to school when they come across, for example, a difficult crossing on the street or an area of heavy traffic.
As expected, the classification of Marfan is not successfully assigned in the first instance as there were only 18 faces of individuals with Marfan in the database (making this an example of a difficult case with the current database).
Rice's example revealed a difficult truth about digital scholarly publishing: it is still expensive.
The role-playing simulator lets them develop their skills by interacting, for example, with a difficult client who is being aggressive on pricing.
The design of an optimal (output feedback) reduced order control (ROC) law for a dynamic control system is an important example of a difficult and in general non-convex (nonlinear) optimal control problem.
They did, however, acknowledge the genius of this person, who could, for example, read a difficult book of mathematics for the first time, and then explain it — in his savage manner — a short while later.
This puts the nominalist who wishes to exclude the existence of sets and non-Euclidean geometry, but to include the existence of quarks and other undetectable entities of physics, for example, in a difficult position.
The four-gene cycle (genes 5→6→8→7→5, Fig. 8A) in network 5 is an example for a difficult network motif that our approach predicts correctly only if the multifactorial data is included.
Inflammatory arthritis (IA), defined as a group of chronic rheumatic diseases, including rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis, is an example of a difficult diagnosis to make.
As an example of a difficult region to assemble, the major histocompatibility complex (MHC), which has an important role in immunity, was broken into over 60 contigs in the Illumina assembly, while 97% of the region was assembled in just two contigs using PacBio sequencing.
