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Function prediction methods can be extended using gene context analysis approaches such as examining the conservation of chromosomal gene clusters, gene fusion events and co-occurrence profiles across genomes.
Examining the conservation of other genes involved in cell wall structure revealed expansions specific to W. dermatitidis.
Our results further suggest that considering sub-clinical disease may be critical when examining the conservation of declining populations.
The significance of these absences is not known, but we are currently examining the conservation of other ESCRT-II components in these species.
By examining the conservation of cleavage sites in protein substrates in terms of peptidase substrate binding sites, it is clear that there are a number of cleavages where atypical replacements occur.
Examining the conservation of functionally enriched network patterns we find that functionally enriched patterns have significantly low mean conservation score and significantly high conservation coherency score (Z-score > 2).
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To examine the conservation of these conserved, common group B targets on an expanded evolutionary scale, we compared them with the targets of the mouse group B Sox proteins Sox2 and Sox3 and the group C Sox protein Sox11 (Table 5).
Further, all five PLEs contain a putative LSR and respond to ICP1 infection by circularizing following infection20, therefore we examined the conservation of the Int/PexA interaction.
To ask the biological significance of antisense transcription mediated downregulation of sense gene's protein production in an evolutionary view, we examined the conservation of DNA sequences near the distal pA site of RNASEH2C in multiple species.
We examined the conservation of sequential measurements of each of the selected patients against the corresponding CD4+ T-cell count.
We carried out a phylogenetic analysis to examine the conservation of the N-terminal extension of SF2/ASF (Figure 2).
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