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This dose of MCP previously led to effective galectin-3 blockade and was non-toxic in murine cancer studies examining parameters such as tumour growth, angiogenesis and spontaneous metastasis [24].
Importantly, PPA detects changes in the interrelationships between parameters, which can be missed when examining parameters individually against population statistics.
Currently, the most common ways of evaluating embryo quality non-invasively are by examining parameters such as morphology and cleavage rate.
For both state-spaces we chose α = 1.8 for the parameter of the Γ-distribution, based on a preliminary study examining parameters inferred from PANDIT families (Whelan et al. 2003, 2006).
The differences in success rates for discovery efforts as determined by this effort can provide insights for future SNP development efforts by examining parameters and pipelines used and the outcome of those discovery sets.
Among approaches for evaluating STMMs, most researchers have focused on the quality of the host and visiting mission teams, examining parameters such as costs, efficiency, education, preparedness, and sustainability [ 11, 20– 29, 29– 329.
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Convergence between runs and attainment of stationarity was runs was further comfirmed by examining parameter distrubutions in Tracer v1.6 (Rambaut et al. 2014).
Convergence of parameters was checked by examining parameter means and variances between runs.
The results tab (Fig. 11) offers an interface for comparing the model fit of all models simultaneously (A), examining parameter estimates (B), and making pairwise comparisons between parameters.
In practice, it is usual to specify different architectures or hypotheses and formally compare the evidence for these models, before examining parameter estimates [ 38].
We checked for stationary posterior distributions, ESS above 200, and convergence between runs by examining parameter traces with the program Tracer v1.6 [ 49].
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