Here, we identify genes that are induced or repressed by FruM by examining gene expression in adult head tissues where we over-express individual FruM isoforms (FruMA, FruMB and FruMC) in fru P1-expressing neurons of either males or females.
We used R-STAT analyses to identify a list of potentially differentially expressed contigs, in order to provide direction for future studies examining gene expression within or across life cycle stages of B. terrestris.
A recent third microarray study[ 61] examining gene expression in a time course of parasite differentiation revealed many of the differentially expressed genes identified here were common to all studies.
However, as the severity of diseases can be exacerbated by non genetic factors, the ability to predict disease severity by examining gene expression alone may be inadequate.
By examining gene expression patterns, insertional mutants and cross-species complementation studies, we find evidence that FAMA function is conserved between monocots and dicots, despite their different stomatal morphologies, whereas the roles of MUTE and two SPCH paralogs are somewhat divergent.
Traditionally, the elucidation of genes involved in maturation and aging has been studied in a temporal fashion by examining gene expression at different time points in an organism's life as well as by knocking out, knocking in, and mutating genes thought to be involved.
A second project, in collaboration with Steve Haase, is examining gene expression during the erythrocytic cycle in P. vivax.
Together, these studies highlight the importance of examining gene expression from the primary tissue involved in neuropsychiatric conditions-the cortical brain.
Although the application of SCS to study the immune system is limited at present, SCS has shown robust potential for defining immune cell subpopulations and for examining gene expression variability, differential splicing and gene-regulatory networks [89].
In the past, many studies of the biological consequences of sleep restriction were conducted in laboratory animals like mice, with scientists examining gene expression in tissues from the brain or the liver.
We then tested the Wg antagonism hypothesis molecularly by examining gene expression in third instar wing disks.
