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Furthermore, this study examines compounds that have clinical relevance and expands the copper enrichment studies.
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Among the tested compounds examined, compounds 3 7 showed significance difference from the standard drug ciprofloxacin.
The established hot plate method is considered to be selective to examine compounds acting through opioid receptor [41].
All examined compounds are of typical layered structure at room temperature.
All the 67 examined compounds showed high MAO-B selectivity, some of them achieving potency in the low nanomolar range.
The N-para-fluorophenethyl derivative had the highest μ-opioid receptor affinity of the examined compounds (Ki = 0.35 μM).
Due to their long alkylester and alkylamine terminal groups the examined compounds were well soluble in organic solvents.
The 2, 2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging ability of the examined compounds was measured according to Brand-Williams, Cuvelier, & Berset [20].
By examining compounds 2, 3 and 4, it was found that their MS all exhibited the protonated molecular ion at m/z 207.
IE% values of the examined compounds on Cu (111) surface followed the order arrangement: BPP_1 > BPP_2 > BPP_3 > BPP_4 > BPP_5 > BPP_6 > BPP_7.
Antibacterial and antifungal screening revealed that some of the examined compounds demonstrated fair to excellent antimicrobial activities relative to Ciprofloxacin and Fluconazole; standard potent antibacterial and antifungal, respectively.
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