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When all 20 metaphases examined were normal or when at least 18 metaphases were normal with one or two demonstrating a non-clonal, simple chromosome loss (which is most likely a technical artifact), the cell line was concluded to have normal karyotype.
All other organs examined were normal.
The Mtor chino mutation alone resulted in a decrease in numbers of splenocytes, including CD4+ cells, as was observed in mice with reduced Mtor mRNA (Zhang et al., 2011), but the relative proportions of the CD4+ subsets examined were normal.
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The cells that we have examined are normal bladder epithelium, normal bladder epithelial cells that have been immortalized with hTERT, a cell line derived from a non-invasive bladder cancer (RT4) and cell lines derived from invasive bladder cancers (T24 and UMUC3) [ 18].
The bone marrow was deep red, the parotid lymph nodes were moderately enlarged and all of the lymph nodes examined were slightly larger than normal.
Moreover, with regard to the SDQ component scores, all members of the particular case group examined were observed to have Normal Emotional Symptoms, Hyperactivity, and Prosocial scores.
All normal tissues examined were obtained from three autopsy cases.
Following imaging, the tissue specimens were placed in buffered formalin and submitted for histopathology, showing that 5 examined specimens were normal, 6 specimens exhibited precancer (3 adenomatous polyps, 3 adenoma), and 8 specimens showed cancer.
All three muscle groups examined are important for normal gait and strength deficiencies in any group affect gait and gait speed.
The rank order of OPase activity in extracts of 24 normal tissues examined was kidney > lung, breast and colon > ovary.
The distribution frequency of the examined characters was normal or only slightly left- or right-biased (data not shown), which enabled further statistical analyses.
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