We did not examine off-label prescribing by age, dosage, duration, or route of administration.
To examine off-target effects of gene-silencing in our cells, we performed a qRT-PCR of Interferon beta and STAT1.
To examine off-target gene-silencing in our cells, we used the BLAST database (www.ncbi.nlm.nih.gov/BLAST) to search the human genome for any complementary sequences with at least 11 contiguous nucleotides matching the RNAi sites we used.
He is also shopping around a documentary series he produced, "The N.F.L.: The Gift or the Curse?" One of the episodes in the series, which examines off-the-field issues, is about concussions and their effects.
To that end, we examined off-duty Navy SEALs while performing a simple emotion face-processing task during functional magnetic resonance imaging (fMRI), and compared them with healthy male volunteers.
Radley and co-workers [1] examined off-label prescribing patterns of office based physicians, distinguishing treatments as having strong or limited scientific support and found that the greatest disparity between "supported and unsupported" off-label prescriptions occurred among psychiatric therapies (4% strong support vs 96% limited or no support).
One study was not enrolled as it examined off-label infliximab therapy (3 mg/kg) [ 17].
Thereafter LFPs were examined off-line in Spike2 software (Cambridge Electronics Design, Cambridge, UK).
In these cases the experimental session was re-examined off-line with a newly adapted rejection mode.
Two studies examined off-road bike paths and found reduced risks, ranging from 0.11 to 0.67 times the risk of cycling on minor roads [ 64, 67].
Eye fixation and arm movements were examined off-line from videos recorded using an MR-compatible infrared-sensitive camera (MRC Systems GmbH, Heidelberg, Germany) positioned underneath the fixation LED and directed toward the subject's eyes and hand.
