Whether A or B would conduct the first examination was randomized by envelopes, which were prepared by an independent statistician and opened immediately before the first test.
Eligible pregnant women from the West Kiang region of The Gambia (pregnancy dated by ultrasound examination) are randomized on entry to 4 intervention groups (Iron-folate (FeFol = standard care), multiple micronutrients (MMN), protein-energy (PE), PE + MMN).
An incomplete Latin square design was used such that order of the examiners was randomized to balance and minimize examiner's examination order effects.
After the preoperative examination, patients were randomized into two groups based on type of OVD used during phacoemulsification: Viscoat or Visthesia.
18 882 men over the age of 55, with a PSA of 3.0 ng/ml or lower and a normal digital rectal examination (DRE) were randomized to receive 7 years of finasteride (5 mg) or placebo daily.
After completing baseline examinations, the participants were randomized and informed of group allocation.
After the baseline examination, the children were randomized to one of two parallel groups, test or placebo, with the aid of computer-generated numbers (Excel randomization tool) that were kept in sealed envelopes to ensure allocation concealment.
Children and adolescents (ages 9 16 years at enrollment) who were healthy based on medical history and physical examination at enrollment were randomized in a 2 1 ratio to receive three subcutaneous injections of CYD-TDV or three subcutaneous placebo injections (NaCl 0.9%) at 0, 6, and 12 months.
After completion of the baseline test the patients were randomized by persons not involved in the examination.
In this 24-week, double-blind, multinational study (NCT00322153), outpatients with AD (Mini-Mental State Examination scores of 3 14) were randomized to receive once-daily, 28-mg, extended-release memantine or placebo.
