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The optimal microspheres were evaluated with respect to zeta potential study, drug release kinetic study, ex vivo permeation study, histological examination, stability study and in vivo study.
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Some optimal strategies based on genetic algorithm (GA), such as individual validity examination, structural stability examination and system controllability examination, are adopted to guide the optimization process efficiently.
The outcomes have been achieved through both an analytical examination of stability, as well as a computational investigation to provide insight where analytical theory is questionable.
The developed algorithm was then used to perform a high-throughput analysis of over 2000 femora in a genetic linkage study for further examination of stability and performance.
The accuracy of immediate examination of stability under anesthesia is very reliable [ 3].
Physical examination assessed stability (sulcus sign, load and shift test, anterior and posterior drawer tests) of both operated and contralateral shoulders [ 17- 19].
Many women with adnexal masses can be reassured that they need no further follow-up and many more can be reassured after one further US examination showing stability or regression of the mass.
Examination of electrical stability for 5% doped IBZO and ISZO devices made at 200 °C also showed remarkable stability with slightly higher threshold voltage shifts of 1.9 and 2.7 V, respectively.
The possibility of sample degradation was considered but discounted after an experimental examination of rotavirus stability and EM visualization of rotavirus-like particles in several untypeable samples.
However, SPS requires a careful examination of the stability and dispersion of the feedstock suspensions in order to produce high quality coatings.
The origin of the theory of moment equations and their use in the examination of the stability can be found in the works by Valeev [4] and his scientific school (e.g., [18]).
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