The ultimate identification of bone tumours, however, rests on examination of tissue samples.
Polyclinics usually have X-ray apparatus and facilities for examination of tissue specimens, facilities associated with the departments of the district hospital.
Examination of tissue removed from the tumor during surgery or CT scan-guided biopsy is used to confirm the exact type of tumor.
Perales for assistance with intracellular cytokine staining; H. Nguyen for expertise with the histopathologic examination of tissue specimen; G. Heller for statistical help; and R.J. O'Reilly and A. Houghton for helpful discussions and support throughout the project.
Cytomegalovirus infection in neonates was determined by means of urinary viral isolation during the first week after birth or the histologic examination of tissue from aborted fetuses.
The removal and examination of tissue or other material from the body (biopsy) is used to diagnose the nature of abnormalities such as tumours.
This approach facilitates advances in personalized medicine where, for example, molecular markers found in the laboratory examination of tissue predict outcomes that help determine the type of chemotherapy that should be given to an individual patient.
Re "For Breast Health, Take the Initiative" (Personal Health, Oct. 21): Prospective comparisons of mammography with other imaging modalities like M.R.I. and PET, confirmed by examination of tissue specimens, suggest that more than half of cancers will not be recognized at mammography.
Histologic examination of tissue: Organs of athymic male mice stained with hematoxylin and eosin, trichrome, or giemsa were microscopically examined by a mouse pathologist (L.L.) in a blinded fashion, and toxicity scored using an established semi-quantitative histological scoring system38 (Supplementary Fig. 8).
Pathologic examination of tissue showed microsporidia.
Fig. 4 Histological examination of tissue specimens.
