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These studies represent a comprehensive examination of the host endothelial transcriptome during lytic infection by KSHV, using methods that allow quantitative assessment of the magnitude and scope of mRNA abundance changes as infection progresses.
Qualitative examination of the host anatomical response to the presence of hNPCctx or hNPCctx-GDNF revealed substantial preservation of the photoreceptor outer nuclear layer (ONL) overlying all subretinal donor cells (Figure 5E and F), with photoreceptor rescue gradually declining outside the distribution of the transplanted cells (Figure 5E and G).
A closer examination of the host cell mitochondria in E. cuniculi-infected cells revealed that mitochondria appear to be closely applied to the PV (Fig. 1A C).
A similar interpretation of the NCLDV evolution was given previously on the basis of the examination of the host ranges of the major lineages of these viruses [ 4].
Histopathologic examination of the host corneal button revealed stromal edema, thickening and excrescences of Descemet's membrane, and a decreased number of endothelial cells, consistent with Fuchs' corneal dystrophy.
After macroscopic examination of the host liver, the tissue samples with pathological changes were fixed in 4% buffered formaldehyde (for hematoxylin-eosin staining) or Bouin's solution (for Gomori trichrome staining) and embedded in paraffin according to standard procedures.
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Several studies have also analyzed parasite expression patterns in vitro and in vivo [ 17, 18]; however, concurrent examination of the host-parasite interaction has only been used to analyze the vector-parasite relationship between Anopheles stephensi and P. berghei [ 19].
On examination of the 91 host-associated bacteria lacking a complete pathway in detail [Additional File 1], most (67/91) had lost five or more of the genes encoding enzymes of the shikimic acid pathway, whereas nearly all of the rest (20/91) have only lost a single enzyme.
Surprisingly, examination of these host-derived genes revealed that several are constituents of the core genes of the NCLDV family [ 10].
We chose to examine CIA as a well-defined model of autoimmune arthritis that allows an examination of the role of host immune response to an autoantigen, in this case CII.
Although no systematic examination of the role of the host cell environment on rates of de novo HAC formation has yet been reported, it remains formally possible that the cis-acting effects of adjacent genomic loci on de novo HAC formation are contingent on certain cellular environments.
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examination of the district
examination of the uterus
examination of the evidence
examination of the door
examination of the record
examination of the history
examination of the back
examination of the commonplace
examination of the debate
examination of the band
examination of the case
examination of the difference
examination of the packaging
examination of the bullet
examination of the thuggish
examination of the period
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