The examining dentist showed high intra-and inter-examination consistency (kappa = 0.91 0.83).
Because of this, our examination of consistency implicitly assesses the reproducibility of eQTL between labs.
This simple type of genomic aberration allows for examination of consistency at the level of probe log-ratioss (or potentially segmented means) along the whole chromosome.
Examination of consistency of findings across multiple clinical endpoints in a proof-of-concept study may be useful in identifying efficacious therapies, and in selecting a dose from among several tested.
While systematic reviews of hormone replacement therapy may be valuable for an examination of consistency and additional outcomes, the WHI alone is a sufficient basis for many clinical decisions.
Furthermore, to assure a careful and reliable measurement, examinations of consistency indicated by inter-rater agreements are needed [ 25].
Here we present the first systematic examination of the consistency between eQTL obtained independently from the BXD and MDP populations.
The reliability of each identified dimension was assessed by examination of internal consistency and reproducibility.
Validation of the model by bootstrapping and examination of internal consistency strengthened the above results.
Examination of internal consistency confirmed a trend in an increased CRC risk associated with the predisposing combination patterns, regardless of the mode of stratification used [Additional file 5].
The examination of internal consistency, reliability of item responses and convergent and discriminant validity shows substantially lower reliability and validity for the phone survey method.
