Sentence examples for exaggerated tissue from inspiring English sources

Abnormal or exaggerated tissue responses may lead to further loss of function instead of restoration.

Furthermore, the same study showed an increased production, differentiation and activation of granulocytes in miR-223 deficient mice, resulting in inflammation and exaggerated tissue destruction.

In the context of fibrosis, exaggerated tissue injury may result from excessive M1 activation, whilst inappropriate M2 activation may drive exaggerated myofibroblast responses.

This conclusion is based upon observations in a miR-223 knockout mouse, which demonstrated increased neutrophil numbers, spontaneous inflammation in the lung and exaggerated tissue destruction following LPS challenge [ 17].

On the basis of this result, similar to the findings of the study by Rogliani et al cited above, interstitial fibroblast activation could be stimulated to a greater degree in the areas of lung destruction in CPFE compared with emphysema alone, as in exaggerated tissue remodelling.

Although obesity promotes systemic inflammation, we find activation of the inflammation-associated Mitogen Activated Protein kinase ERK occurs specifically in adipose tissues of obese mice, and provide evidence that adipocyte ERK activation may explain exaggerated adipose tissue lipolysis observed in obesity.

On the other hand, this case presented intense acute inflammation of unknown cause; some kind of strong infection or immunological response might have triggered the atraumatic rupture of the exaggerated splenic tissue.

Our ROD model exhibits hyperglucocorticoidemia, exaggerated GC tissue reactivation and increased diabetes-related blood markers, all of which are present in humans and rodents with overt T2DM.

This obesity related to exaggerated sepsis-induced tissue injury response is linked to inflammation, and obesity-related disorders are well known to be associated with low levels of adiponectin.

In highly proliferative tissues, this effect would be greatly exaggerated and these tissues would be expected to show the most severe disorders, hence the prevalence of pathologies in the bone marrow, gut and skin.

Decreased or absent neural input will increase the set point with exaggerated proinflammatory responses and tissue damage, whereas increased input results in inadequate immune defence.