Exact(7)
An exaggerated release of bradykinin, which is activated by products of the amniotic fluid that enter the maternal circulation, could explain the symptoms that are present in amniotic fluid embolism.
We exposed primary murine microglia to a pharmacological γ-secretase inhibitor which resulted in exaggerated release of TNFα and IL-6 in response to lipopolysaccharide.
Animal studies of ileal transposition show exaggerated release of the gastrointestinal hormone glucagon like peptide-1.
This exaggerated release of inflammatory cytokines is responsible for the clinical signs of illness associated with these toxins [ 10, 11].
Nitric oxide, in turn, promotes the exaggerated release of excitatory amino acids and substance P from presynaptic afferent terminals and causes the dorsal horn neurons to become hyperexcitable.
For example, in response to duodenal nutrient, there is a greater degree of antral hypo-motility, pyloric hyperactivity [ 27], and exaggerated release of both CCK and PYY in critically ill patients [ 28, 29].
Similar(53)
Fox's irritation with Icebox was only partly based on the exaggerated release.
This results suggest that stimulation with P. acnes leads to an exaggerated local release of cytokines necessary for granuloma and multinucleated giant cell formation, the typical histopathological changes observed in sarcoidosis [ 23, 24].
We hypothesized, however, that cytokines secreted by the host during ARDS may indeed favor the growth of bacteria and explain the association between an exaggerated and protracted release of cytokines and the frequent development of NIs.
ABPA is characterized by an exaggerated Th-2-mediated response triggering release of inflammatory cytokines and growth factors leading to airway hyperresponsiveness, goblet cell hyperplasia, and subepithelial fibrosis [ 13, 14].
The occurrence of clinical complications such as intrauterine growth retardation (IUGR), maternal diabetes, hypotension, cerebral ischemia, and reperfusion during this life period may lead to an amplified release of vasoactive molecules, inducing exaggerated cell death and tissue damage.
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