The term has traditionally been used in studies of anxiety and panic disorders to describe a cognitive attitude characterized by an exaggerated patient focus on physical symptoms, magnification ("somatosensory amplification"), rumination, and beliefs of catastrophic out-comes [3].
Animal and in vitro studies have suggested that Treg cells may play a role in the suppression of the Th2 response often found exaggerated in patients with allergic disease [ 59, 60], and that this suppression mechanism may be flawed in allergic patients [ 61, 62].
Moreover, there was no evidence from this sample to support the idea that eye movements become more or less exaggerated in patients compared to controls during the sequence of the film where a hazard was present or emerging.
Critically, our data do not imply that habit formation is exaggerated in patients with OCD.
Possibly this initial inflammatory reaction is exaggerated in patients who are prone to develop postoperative delirium.
It is likely that the complex spatial variability we observed in healthy controls is more exaggerated in patients with brain damage.
The age-related progressive bone loss is exaggerated in patients with osteoporosis, a disease characterized by decreased bone mass, increased bone fragility, and increased risk of fractures [ 1].
The negative clinical effect of this apparent under-use of exercise use may be further exaggerated if patients are unable to translate advice or instructions into correctly executed and frequently performed exercises.
This could be because of earlier diagnosis through screening in antenatal clinics 28 before women have a low CD4 count, late presentation in men, 29 or sex differences in lifestyle factors that are exaggerated in patients (for example, smoking, alcohol, and drug misuse are common in men who have sex with men but not in women from sub-Saharan Africa).
Corpus callosum changes are mainly located in the interhemispheric motor fibres of the body (Chapman et al., 2013), and seem exaggerated in patients with primary lateral sclerosis which are considered part of the spectrum of ALS in the wider use of the diagnostic term (Ciccarelli et al., 2009; Agosta et al., 2013).
