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The second insult (infection or ACS) further exaggerated this response, leading to MOF and mortality.
The Queensland tourism industry raised questions about the reliability of the survey, saying scientists had previously made exaggerated claims about mortality rates and bleaching.
If education levels of the census were more inflated than those of death certificate data, exaggerated educational mortality differentials could be made.
However, in response to myocardial infarction (MI), these mice suffer exaggerated cardiac damage and increased mortality compared with wildtype (WT) mice.
Exaggerated exercise blood pressure (BP) predicts mortality.
This finding was not driven by differential mortality where individuals with an exaggerated immune response were selected away in the parasite free environment, because we did not find an interaction between methionine supplementation and hen flea manipulation on mortality.
The results are far too exaggerated [ 22, 85], and treatment-related mortality "was related to lack of experience with high-dose treatment".
We debunked the exaggerated finding by tracking 12 years of hospital mortality data before the campaign started, where we found no change in the already declining mortality trend.
The methionine oxidation of CamKII is reversible by methionine sulfoxide reductase A (MsrA) and mice deficient in MsrA were found to exhibit exaggerated CamKII oxidation, cardiomyocyte apoptosis, cardiac dysfunction, and mortality after myocardial infarction [128].
If this extreme inflammatory response is not counterbalanced by a competent compensatory anti-inflammatory response syndrome, the resultant exaggerated inflammatory response leads to increased morbidity and mortality during sepsis [ 14].
Herzig and colleagues' findings clearly show the detrimental side of exaggerated CXCR3 signaling in severe sepsis with high mortalities.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com