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Inadequate reporting and design of RCTs are associated with bias, especially exaggerated intervention or treatment effects that influence the interpretation of the findings of RCTs in helping to develop clinical guidelines and in being used for meta-analyses [ 16- 18].
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Empirical evidence found exaggerated estimates of intervention effect in trials with inadequate sequence generation or allocation concealment, 11 12 13 lack of blinding, 11 14 or exclusion of patients from analyses.
These problems will leave many readers confused, often with an exaggerated perception of how well interventions work.
In implementing interventions such as reported here involves some cost but the cost of this intervention should not be over exaggerated because in the long run it may be cheaper to implement these activities to diagnose and treat patients early as outpatient than to receive them late and keep them on admission, which may require surgical interventions in some cases.
Individual-level interventions that help to reduce exaggerated work salience might create a buffer against the effects of work-family conflicts on health.
77 79 Empirical studies show that the effects of experimental interventions measured as odds ratios are exaggerated on average by 21% if allocation concealment is unclear or inadequate and by 18% if trials are not reported as "double blind".
Delayed tPA intervention drastically increased the risk of HT and exaggerated ischemic injury.
Intimal hyperplasia (restenosis) is an exaggerated healing response leading to failure of half of vascular interventions.
Exaggerated fears of the impact of globalisation on workers in industrial countries go hand in hand with a new agenda for intervention at the global level.
But these are exaggerated.
An exaggerated comparison?
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com