Sentence examples for exact toxicity from inspiring English sources

Simulation study and application of EID to the data of a real Phase I trial demonstrate that EID can always estimate a more accurate maximum tolerated dose (MTD) according to the exact toxicity profile under any toxicity profiles without additional cost or length of the trial.

Additional research is required to investigate the exact toxicity mechanisms to deeply elucidate the sensitivity of bacteria to ZnO-NPs, as the results to date are quite promising.

Thus, further investigation is required to assess the toxicity effect of silver nanoparticles in in vivo condition for evaluating its exact toxicity to human and animals.

Though, the antibacterial activity of ZnO-NPs has been referred to a number of issues, but the exact toxicity mechanism is not completely illuminated and still controversial, as there are some queries within the spectrum of antibacterial activity requiring deep explanations.

However, due to differences in structures and diverse pharmacological effects, the exact toxicity mechanisms exerted by quinones are far from elucidatation.

The exact toxicity profile of the laboratory attenuated strain of EMCV has yet to be determined in non-human primates but these future studies could further aid in the clinical development of this oncolytic virus candidate.

While the exact toxicities of long-term overexposure are still completely unknown, a recent study by Das et al. [79] looks at the potential toxicity to mammalian germ cells and developing embryos from engineering nanoparticles such as gold, silver, fullerenes, and chitosan.

Data regarding the exact NPS toxicity are still limited.

Whereas ω values can directly reflect the toxic potencies of aldehyde electrophiles, the exact correspondence of toxicity to this parameter can be lower than expected since other physicochemical characteristics of the toxicant can modify the rate of the adduct reaction.

Till today, the exact mechanism and toxicity of green silver nanoparticles to bacteria is an elusive question.

While the exact mechanism of toxicity is unknown, the prostaglandins are transported into the nucleus [60] [62] where the electrophilic α,β-unsaturated carbonyl is free to bind with nucleophilic sulfhydryl residues on target proteins, unless rapidly conjugated by cytosolic GSH and transported out of the cell by glutathione-conjugate transporters [63].