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Comparing the boys' genome sequences helped uncover the exact mutation that causes the disease.
This novel CRISPR/Cas can expand the feasibility of the zygote-mediated generation of genome-modified animals that require an exact mutation design.
The researchers haven't yet found the exact mutation responsible for the worm resistance and asthma susceptibility.
But despite decades of research, scientists didn't know the exact mutation responsible for the once-unusual dark wings.
But the story had an unsatisfying ending: Despite decades of research, scientists didn't know the exact mutation responsible for the once-unusual dark wings.
These results demonstrate that the TaqMan probe-based FMCA with color multiplexing can be used to identify the exact mutation type with combined probes in one reaction.
Similar(33)
Genetically screening other breast tumor tissue samples revealed that none shared the exact mutations identified in the original patient, although some samples contained mutations in the same gene.
Not only have we pinpointed the cause, down to the exact mutations in DNA, but we can stop the disease occurring.
In the end, the researchers sequenced the genomes of the best lycopene producers to identify the exact mutations that boosted the output.
Knowing the exact mutations that make the virus transmissible also enables scientists to look for them in the field and take more aggressive control measures when one or more show up, adds Fouchier.
Publishing the exact mutations the virus needs in order to spread among mammals could guide research on defensive measures and help derail an emerging pandemic, but many fear that the knowledge could help bioterrorists start one.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com