Sentence examples for exacerbation significantly from inspiring English sources

In the INPULSIS-2 trial, the time to the first acute exacerbation significantly increased in IPF patients who were treated with 150 mg of nintedanib twice daily.

Participants who were free from exacerbations significantly increased over placebo (OR = 2.81, 95% CI: 1.85 to 4.26, P value <0.001).

Thus, the above two types of regression analyses (Additional file 1, Tables S1 and S2) confirmed that the frequency of exacerbations significantly affected the decline in health status.

Logistic multiple regression analyses confirmed that the exacerbations significantly influenced the Fatigue and Mastery domains of the CRQ, and the Symptoms in the SGRQ.

There were no differences in FEV1% predicted up to 1 year postoperatively, but hospital admissions secondary to pulmonary exacerbations significantly decreased (2.0 ± 1.4 versus 3.2 ± 2.4, respectively; p < 0.05).

Multiple regression analyses confirmed that the exacerbations significantly predicted the changes in the Mastery of the CRQ and Symptoms of the SGRQ, independent of their baseline scores, and logistic regression analyses confirmed a statistically significant effect of the exacerbations on the health status deterioration in the Fatigue and Mastery of the CRQ and the Symptoms of the SGRQ.

Following the baseline scores, the frequency of exacerbations significantly accounted for the changes in the Mastery of the CRQ (R2 = 0.03) and the Symptoms of the SGRQ (R2 = 0.05), and the RV/TLC accounted for the changes in the Impacts of the SGRQ (R2 = 0.03).

And we found that the number of participants free from exacerbation was significantly greater, and the number of participants who had at least 3 exacerbations was significantly less in macrolide-treated group compared with control group.

Time to first exacerbation was significantly extended in the 6-month (p=0.028) [ 46] and 1-yr study (p<0.001) [ 71].

In addition, time to a first exacerbation was significantly prolonged in patients taking macrolides compared with placebo.

In our study, patients with COPD exacerbation had significantly lower IGF-I levels on D1 and also on D15 compared to healthy controls.