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MG exacerbation rate was reduced by 75% from the year before REGAIN (p<0.0001).
Secondary outcomes included spirometry, impulse oscillometry, exacerbation rate, airway biomarkers, systemic inflammation, leukotriene biosynthesis and T-lymphocyte function.
Studies have shown that ambient UFPs have detrimental effects on both the cardiovascular and respiratory systems, including a higher incidence of atherosclerosis and exacerbation rate of asthma.
Primary outcome is exacerbation rate.
The primary outcome will be exacerbation rate.
The exacerbation rate per patient per year was not reported.
Hence, a reduced exacerbation rate is associated with higher savings.
Nevertheless, pharmacotherapies have a proven impact on reducing the exacerbation rate in COPD [ 16].
Our results showed that exacerbation rate was associated with impairment of HS during follow-up.
11 Also, the exacerbation rate and P. aeruginosa sputum count decreased.
Differences in exacerbation rate and hospitalization rate were calculated using Poisson regression.
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