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Of the two subjects who withdrew due to AEs, one had an asthma exacerbation on Day 5 and one subject developed a flu'-like illness on Day 36; neither AE was considered by the investigator to be related to study drug.
1.2 To study prospectively the effects of a COPD exacerbation on resident loved ones' perceptions of patients' health status and problematic ADLs.
3.1 To study prospectively the effects of a COPD exacerbation on resident loved ones' perceptions of patients' mood status, care dependency and daily symptoms.
Therefore, the primary objectives of this study are to investigate the differences between patients with COPD and resident loved ones' perceptions of patients' health status and problematic ADLs and to study prospectively the effects of a COPD exacerbation on resident loved ones' perceptions of patients' health status and problematic ADLs.
Furthermore, this study investigates the impact of a hospitalisation due to an acute COPD exacerbation on the resident loved ones.
However, patients who have not experienced an exacerbation may not rate avoidance of an attack as highly as those who have suffered one, possibly because of the pronounced impact of an exacerbation on quality of life[ 26].
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Within the first few days I was forced to tell a few more people about CF, as I had started the first semester with an exacerbation brought on by hemoptysis (coughing up blood).
This factor was taken into account in our model resulting in 0.8 exacerbations on average per patient during one year, which was in line with the yearly exacerbation frequency in the UPLIFT trial (0.85 in the placebo group).
Many authors have examined the effect of pulmonary exacerbations on lung function [ 7, 8] and have demonstrated that up to one-third of CF patients will not recover their baseline forced expiratory volume in 1 s (FEV1) [ 7].
This study was designed to assess the influence of antibiotic therapy for infectious exacerbations on resting energy expenditure in young patients with cystic fibrosis.
To investigate the impact of pulmonary exacerbations on the health-related quality of life (HRQOL) of patients with cystic fibrosis (CF) and to elucidate factors that are associated with changes in HRQOL post-exacerbation.
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