Sentence examples for exacerbating this phenotype from inspiring English sources

As the atm-1 mutant has increased frequency of apparent telomere to telomere chromosome fusions, which can result in a variable high frequency of males (Jones et al. 2012), we examined whether the loss of CKU-80 was exacerbating this phenotype.

Increasing growth temperature generally exacerbated this phenotype.

Second, the deletion of the γ-globin enhancer by the 118 kb deletion raises the suspicion that its absence may exacerbate this β-thalassemia phenotype.

We propose that elucidation of the mechanism by which hTRM9L activity affects translation and paromomycin sensitivity may allow us to exacerbate this translational error phenotype for therapeutic purposes.

Using this yeast model, the authors perform a comprehensive search for genes that, when inactivated, suppress or exacerbate the phenotype resulting from this mutation.

It was especially striking in this respect that complete deletion of the sortilin gene dramatically exacerbated the phenotype of TrkA deficiency, as TrkA+/− mice were not born in the absence of the sortilin receptor (Vaegter et al., 2011).

Our results, beyond the approach used, provide clear and robust evidence for a wider and ground-breaking concept: forcing regeneration in a structurally impaired dystrophic muscle actually leads to an increase of the oxidative stress and an acceleration of degeneration cycles, which exacerbates the phenotype.

Interestingly, spt16-m, a newly identified Spt16p mutant allele in our group, dramatically exacerbates the phenotype of cac1Δrtt106Δ (77.3%) (Fig. 1C).

Activation of Myc in the presence of TSA exacerbated the phenotype of K14MycER epidermis (Fig. 6D,H,L,P,T).

Supplementation of the diet with a high concentration of Mg2+ exacerbated the phenotype, resulting in growth arrest during the larval period.

Alternately, there could be some form of synergy working with reduced c-CBL levels and mutated receptors that exacerbate the phenotype of each alone.