Furthermore, the inhibition of PARylation in these KD cells, though exacerbating the impact of PARP1 depletion, followed a similar profile to the effect in WT cells.
City analysts said industry's travails were likely to continue in the second quarter of 2016, with the impact of the looming EU referendum exacerbating the impact of weak global demand.
Chinese ego repression ensures that individual identities are linked to national pride, exacerbating the impact of American condescension, real or imagined.
The environment, in its broadest sense, will often influence clinical penetrance, either ameliorating or exacerbating the impact of heritable genetic variants (Hunter 2005).
In contrast to Canada, adjusting for trends in demographics and health care substantially changed our excess death estimates, exacerbating the impact of the 1951 epidemic.
The review has shown that the lack of recognition of needs and poor support from the health and social systems further compromise socioeconomic status, activities of daily living, social participation and personal development, thereby exacerbating the impact of the illness in their lives.
"Human efforts to mitigate," Dr. Minshall said, "exacerbate the impacts" of the fire.
Sea-level rise will exacerbate the impacts of storm waves on atolls' coral reefs by reducing wave breaking at the reef crest and increasing the water depth relative to the hydrodynamic roughness over the reef flat.
Such anthropogenic disorders have been shown to exacerbate the impacts of climate change on people and ecosystems (Mertz et al. 2009a; Raworth 2007).
While it is difficult to determine what percentage of any particular drought or other extreme event can be attributed to climate change, steadily increasing average temperatures caused by the rise of greenhouse gases in the atmosphere only serve to exacerbate the impacts of droughts.
