Sentence examples for exacerbates neuronal from inspiring English sources

There is abundant experimental evidence suggesting that fever leads to, or exacerbates, neuronal injury in conditions such as cerebral ischemia and traumatic brain injury.

Thus, M1 phenotype exacerbates neuronal dysfunction by several different pathways, which include, at least, cytokine and ROS production and glutamate excitotoxicity [81, 88].

The ROS-triggered transactivation of TrkB exerts neuroprotective effects, because inhibition of TrkB kinase activity or uncoupling Shc signaling from TrkB exacerbates neuronal cell death induced by H(2 O(2 O

More importantly, neurons from AdAcon transduced cultures revealed greater damage than AdGFP transduced cells at 500 µM PQ2+ supporting that m-aconitase overexpression exacerbates neuronal death upon oxidative inactivation.

Brain hyperthermia markedly exacerbates neuronal injury [ 43].

It is upregulated after ICH and exacerbates neuronal injury.

Hence, HMGB1/RAGE does not exacerbate neuronal inflammation but plays a role in promoting NSCs differentiating into mature neurons in the pathological process of SCI.

Seizures and SE in neonates are often secondary to an underlying neurological disorder and may cause or exacerbate neuronal damage.

Altogether, this data suggests that beta-synuclein changes in DLB may exacerbate neuronal dysfunction caused by accumulation of alpha-synuclein by influencing protein degradation pathways; this should be taken into consideration when designing therapeutic strategies aimed to decrease alpha-synuclein burden in Lewy body diseases.

Activated microglia has been shown to release pro-inflammatory cytokines such as IL-6 and TNFα that could exacerbate neuronal damage.

This disruption of neurotrophin signaling could further exacerbate neuronal injury.