Sentence examples for exacerbates development from inspiring English sources

Renovascular hypertension superimposed on diabetes exacerbates development of chronic renal disease in db/db mice at least in part through interaction with the renin-angiotensin system.

Based on studies demonstrating high VMD2 expression in the testes, and since IL-10 gene expression was 55,000 fold higher in the testes of Tg+ mice, we sought to determine if increased IL-10 gene expression in the testes of male Tg+ mice may exacerbate development of disease compared to female Tg+ mice.

This strongly suggests that loss of negative growth regulation in this model exacerbates cancer development at a very early stage.

To assess whether phacoemulsification cataract surgery exacerbates the development and progression of diabetic retinopathy (DR) in a cataract surgical cohort.

Over-use and misuse of antibiotics exacerbates the development of drug-resistant bacteria, often called superbugs.

In keeping with these observations are data showing that treatment with anti-GITR also exacerbates the development of autoimmune and allergic disorders including autoimmune gastritis [1], experimental autoimmune encephalomyelitis (EAE) [23], experimental collagen-induced arthritis (CIA) and asthma [24].

This observation suggests that the severity of metabolic syndrome exacerbates the development of stones and cancer.

36 Further, lack of skeletal muscle AMPKα2 activity in transgenic mice exacerbates the development of diet-induced glucose intolerance and insulin resistance.

Growing evidence shows that excess generation of reactive free radicals, largely due to hyperglycemia, causes oxidative stress in pancreatic β-cells, which further exacerbates the development and progression of diabetes and its complications [ 37].

There is growing evidence that excess generation of highly reactive free radicals, largely due to hyperglycemia, causes oxidative stress, which further exacerbates the development and progression of diabetes and its complications.

Treatment of PPAR α null mice with fenofibrate exacerbates LVH development in a pressure overload situation suggesting that the benefits observed here are mostly via PPAR α activation [ 37].