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A report by the House of Commons environmental audit committee concluded last year that it made asthma worse, exacerbated heart disease and respiratory illness, and "probably causes more mortality and morbidity than passive smoking, road traffic accidents or obesity".
Most importantly, the substitution of mice with exogenous PTX3 reversed the exacerbated heart damage in the PTX3-deficient mice, hence a potential non-redundant cardioprotective role for this protein.
CTRP9 downregulation by TNF- α-initiated oxidative PPAR γ suppression contributes to the exacerbated heart injury in diabetes.
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Long-term air pollution, from the sooty particles known as PM10s, nitrogen dioxide (NO2) and nitrogen oxides (NOx), it was told, makes asthma worse and exacerbates heart disease and respiratory illness.
However, campaigners believe this would compound London's air quality problems, as although modern diesel cars emit lower levels of CO2, they emit higher levels of oxides of nitrogen (NOx) which can exacerbate heart disease and respiratory illnesses such as asthma.
Hypertension is well known to exacerbate heart failure in patients with preserved ejection fraction [29].
It is plausible, therefore, that PM exposure may exacerbate heart failure (HF).
People with depression may not feel the drive to take their medication or seek help in a timely fashion, researchers said, and previous research has found that depression may negatively influence overall physical and mental well-being, which may exacerbate heart disease symptoms or increase the risk of developing it.
In fact, apelin signaling may augment inhibition of the renin-angiotensin system [42], which is known to exacerbate heart failure when left unchecked.
This indicates that proteinase 3 may exacerbate heart failure and serve as a prognostic marker.
An increase in O3 could cause or exacerbate heart and lung diseases.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com