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Although many authors have focused on common side effects such as headache, nausea, diarrhea, dizziness, and rash, some scientists very recently have shown that long-term PPI therapy has an exacerbated effect on human cognition.
Using cells engineered to express the Crohn's disease non-risk or risk allele of ATG16L1, we interrogated the SNP-gene interaction with CLEC12A to demonstrate an exacerbated effect on antibacterial autophagy in the setting of the disease-associated SNP.
Figure 5 b shows representative colony structures for competing communities with different initial ratios and Fig. 5 d shows the evolution of relative abundance of the communities, both of which illustrate the exacerbated effect from species competition.
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Concentration of IFM in stands on highly productive sites could exacerbate effects (positive or negative), owing to the positive relationship between forest productivity and animal and plant diversity.
We may speculate that a genetic tendency to delay could exacerbate effects of the spring transition to longer days.
In the authors' own earlier studies, they found that stress seemed to exacerbate effects of pollution, which suggests that stress increases susceptibility to environmental exposures.
Further, because SAM synthesis requires methionine, an essential amino acid in humans, dietary methyl insufficiency could exacerbate effects of arsenic on DNA methylation (McCabe and Caudill 2005).
Madeline learns that hating her anxiety and depression only exacerbate their effects.
Fires were less common <600 m from urban areas, and this fire suppression effect exacerbated urban growth effects.
Air travel may have exacerbated this effect.
Rapid de-stocking by retailers exacerbated the effect of falling demand.
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