Our transcriptional data revealed exacerbated down-regulation of Glut4 mRNA in the KO, by more than 2-fold in the aortic endothelium and 4-fold in the muscle endothelium compared to WT (Fig. 3).
Initial tardy response to ozone in Jemalong, exacerbated by down regulation of ascorbate biosynthesis and hormone signaling pathways may be contributing to its sensitivity.
As the crisis in Ukraine has unfolded, exacerbated by the downing of a Malaysian commercial airline jet late last week courtesy of Moscow-friendly rebels, Western countries have been unable to muster any serious sanctions against Russia.
Acid reflux symptoms can be exacerbated when lying down.
The Ruapehu crisis was exacerbated by relatively rigid, top-down, siloed management structures at local and regional levels which did not cope well with the impacts occurring across a complex multi-jurisdictional setting (Paton et al. [1998]).
Industrial production has slowed to the lowest level in six years, and while the slowdown may have been exacerbated by the Olympics shut-down, it has been on a slowing trend for months.
Some indict mark to market accounting standards for contributing to the recent financial crisis by forcing banks to lower the value of assets as volatile markets spiraled down, exacerbating the situation and driving huge write-downs.
Regulatory mechanisms might be activated to down regulate exacerbated inflammatory responses.
Apparently exhausted and exhibiting unpredictable behaviour, probably exacerbated by drink and drugs, he stepped down from a lengthy British tour supporting PJ Proby, and never rejoined the band.
Some scientists argued that the effect of the tsunami was exacerbated by the widespread cutting down of coastal mangrove swamps in both Thailand and India, for example.Some of the Indian criticism seems unfair.
So, cholinergic signalling and down-stream events may be exacerbated in HNSCC and by this means favour tumour growth and/or promote a more aggressive tumor phenotype.
