"We looked for alternative explanations in the data, but the best evidence still indicates that the legal sale exacerbated the destruction of elephant populations across Africa," Sekar said.
After the conquest, the Spanish would have to come to terms with the city's one major urbanistic scourge: its vulnerability to flooding, which was exacerbated the destruction of the Aztecs' delicate but effective regulation mechanisms.
MEXICO CITY – As the death toll continues to rise from twin storms that flooded much of Mexico, government officials are coming under intense criticism for their handling of the crisis, for failing to act on warnings, and for allowing shoddy construction that exacerbated the destruction.
One could argue that higher IFNγ production should confer a better protection against an intracellular pathogen through macrophage activation, although higher inflammation could also contribute to exacerbated tissue destruction that is required for transmission in tuberculosis.
This elicited anti-Gal antibody further exacerbates the destruction of the ECM bio-implant.
Some scientists and engineers have argued that, despite improvements, the current system exacerbates the destruction of fish by degrading their habitat.
In hepatic studies, TLR4 binding to HBV envelope proteins has also been shown to induce the expression and secretion of TNF-α, IL-12, and IL-6 and other proinflammatory factors, which exacerbates the destruction of liver tissue44,45.
In experimental emphysema, impairment of LOX production exacerbates alveolar destruction and emphysema [43].
Reductions in joint loads and inflammatory cytokines, each thought to exacerbate joint destruction, are potential pathways.
This, in turn, upregulates levels of expression of RANKL and interleukin-6, which further exacerbates bone destruction and increases tumor burden [ 30].
Activation of these signaling cascades is a spontaneous protective response of the host that could also exacerbate the destruction of tissues.
