Recent studies also suggest that DCA is involved in barrier dysfunction., While it is unclear if DCA exacerbates barrier dysfunction in cirrhotic patients, our observation of a combination of reduced DCA/CA ratio, reduction in toxic metabolites from key microbial taxa, improvement in cognitive function and reduction in endotoxemia, warrant further investigation.
Twenty years after the end of apartheid, residential location remains largely racially defined, which can exacerbate barriers if health facilities are located far from non-White neighborhoods [ 8].
Illicit drug use may further exacerbate barriers to accessing contraceptives [ 24], although we found that illicit drug use and economic dependence on one's partner were not significantly associated with higher number of pregnancies.
Concomitant addition of MMP-1 with LPS exacerbated the barrier disruption.
Although the precise mechanisms of the protective effect of low tidal volume ventilation are not fully understood, clinical and experimental data suggest that excessive strain and airspace epithelial shear stress amplify lung inflammation, exacerbate barrier disruption, and promote ongoing pulmonary edema formation.
However, many other times, their circumstances were exacerbated by barriers identified under other dimensions of availability, accessibility, accommodation and acceptability.
Exposure to conflict generally exacerbated the barriers to women's uptake of services, mainly through low educational attainment and stronger cultural desire for increased fertility to replace family members lost to the conflict.
However, accumulating evidence demonstrated that VEGF could exacerbate blood brain barrier (BBB) disruption after ischemic stroke.
Furthermore, we found that ingestion of glucose after a primary injury increases the probability of death through a secondary injury mechanism that exacerbates intestinal barrier dysfunction.
Together, these data indicate that ingestion of sugar beyond a certain threshold after traumatic injury increases the probability of death by exacerbating intestinal barrier dysfunction and that the secondary injury mechanism by which sugar promotes death is saturable.
