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"When taken together with reduced funding for local government, and the damaging knock-on effect for social care, this can only exacerbate pressures on the wider NHS which translate into delays and distress for patients and service users".
Thus hidden information at the time of drafting can exacerbate pressures on the constitution later on.
But analysts said GM's own actions would exacerbate pressures facing already fragile suppliers.
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Internationally, the pressure the BBC is under to commercialise its news service, after being given full funding responsibility for the BBC World Service and extra obligations such as funding licence fees for over-75s, will "exacerbate pressure" for the corporation to compete for advertising and sponsorship outside the UK.
Janina Gray, the Salmon and Trout Association's head of science, said: "The water use of the UK shale gas industry could exacerbate pressure on rivers and wetlands, particularly on sensitive water bodies and those already suffering from over-abstraction, such as chalk streams, and this adds yet further pressure on declining fish populations - the Atlantic salmon being a prime example.
AMPKα2 deficiency was shown to enhance myocardial ischemia/reperfusion injury in a mouse model with cardiomyocyte-specific overexpression of a mutant AMPKα2 catalytic subunit [83], and to exacerbate pressure overload induced left ventricular hypertrophy and dysfunction in AMPKα2 knock-out mice [84].
Concern was still expressed, however, about waiting times and the possibility that a primary care intervention may exacerbate pressure on secondary care services.
"It exacerbates pressures in what are relatively small medical teams". Nurses have been placed on the shortage occupation list, which means they are given a priority in international recruitment.
These events, combined with volatile and often elevated fuel prices in recent years, have exacerbated pressures on households already struggling to access basic and social services.
Competition between cultivation and pasture within the reserve exacerbates pressure on grazing, replicating some of the natural resource conflict issues faced outside the reserve.
In addition, humoral, hormonal and/or sympathetic nerve activities further exacerbates pressure and/or volume overload to affect progression of the LV remodelling.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com