Sentence examples for evolving target from inspiring English sources
Genetic background can also shape the phenotypic effects of transgenes, which, over time and among different wild populations, can make risk assessments a continuously evolving target.
Five years in technology is a long time anywhere, and, without suggesting that reddit is a completed project or anything but a continuously moving and evolving target, it was time to move onto something that is less fully formed with room to explore.
Various combinatorial shRNA-expression systems have been shown to delay effectively the emergence of shRNA-resistant HIV-1 in cell culture [15], [36], proving in principle the efficacy of a multiple targeting RNAi strategy against a rapidly evolving target.
Constitutive activation of AKT has been observed in various cancers and represents an evolving target for therapy in cancer.
The biphasic decay of ESA, the sequential analysis described above, and the simulation of Pfr CD spectra argue for the adoption of a parallel evolving target model for interpreting the narrowband transient data.
The effects of RNAi/target mismatches that have implications for specificity and escape of rapidly evolving targets are considered.
Knowledge of tumor-specific metabolic pathway flux, obtainable via the emerging tool of stable isotope-based dynamic metabolic profiling (SIDMAP), identifies metabolic enzyme drug targets which might help to overcome difficulties related to resistance to currently evolving targeted therapies against more narrowly conceived gene or protein targets.
Effective targeting of rapidly evolving targets requires a combinatorial approach, which is analogous to Highly Active Antiretroviral Therapy (HAART) [reviewed by [12], [13]].
In addition, conserved miRNAs tended to regulate rapidly evolving targets, and upstream miRNAs evolved more rapidly than downstream miRNAs.
These results correspond with empirical evidence that genes expressed in testis and accessory gland tissue are rapidly evolving targets of selection.
Or else rapidly evolving RNA viruses might evolve targets that match host miRNAs in order to increase their host specificity.
