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Although the Western Cape has taken evolving steps to institutionalize participatory frameworks through community health committees (HCs), these committees remain informal under the District Health System and have struggled to promote community participation without formal recognition under law.
While the Western Cape has taken evolving steps to institutionalize these participatory processes, with the development of the Draft Policy and most recently with the legislative adoption of District Health Councils, these transitions may signal the decline, demise, or complete reconfiguration of existing structures for community participation, leaving HCs without direction moving into the future.
In contrast, if yeast cells are committed to sporulation, switching back to proliferation under sporulation condition is cellular reprogramming that requires appropriate perturbations; even with reprogramming perturbations, the fate of yeast cells may not be changed if they are very close to complete sporulation (two evolving steps from the sporulation attractors).
Specially, states within 4 evolving steps to the sporulation attractor never evolved to the cell cycle attractor for the wild type cells.
Therefore, to mimic the generation of iPS cell, we examined the reprogramming of the yeast cells committed to sporulation, i.e. cells within 4 evolving steps from any sporulation attractor that cannot evolve to cell cycle attractors by only switching condition.
However, most of the recipes still cannot reprogram cells within two evolving steps to the sporulation attractor.
Similar(52)
That complex societies evolve step by step from simple ones.
They consist of a two-dimensional array of cells that "evolve" step-by-step according to the state of neighbouring cells and certain rules that depend on the simulation.
The neat family trees and branch lines charting the steady progress of evolution, and those ubiquitous illustrations of the ascent of humans, in which we evolve step by step from bent-over apes to straight-backed homo sapiens, are not just simplistic, they are a profound misshaping of the truth.
Instead, it evolved step by step over hundreds of millions of years.
This initiative, as will be described in the paper, evolved step by step.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com