Exact(6)
Despite structural and functional conservation, divergence between Arabidopsis and monocot clock genes is suggested by evolving functions in the PRR7 lineage in monocots.
Whether any of these pseudogenes are expressed is unclear; however, olfactory receptor loci were detected as being recently duplicated within the bovine genome [ 79] suggesting that they may also be under strong selection for newly evolving functions.
Furthermore, gene duplications within the beef cattle genome tend to encode genes that interface with the external environment such as olfactory receptors [ 36], suggesting that they may be under strong selection for newly evolving functions.
The terms with low Ka/Ks ratio probably represent the most conservative functions, and the terms with high Ka/Ks ratio likely represent the rapidly evolving functions between the two species [ 10, 35].
Parasites have been proven capable of evolving functions beneficial for the metabolic system, and thus also for themselves: they can acquire new catalytic activities which may improve metabolic efficiency, or they might evolve a slightly better replicase activity than previously available [ 3], and thus increase the replication rate of the whole replicator community [ 5].
Furthermore, estimates of synonymous and nonsynonymous substitution rates (dN /dS) suggest that the emergence of relaxin-1, INSL4 and INSL6 during mammalia was driven by positive Darwinian selection, hence these peptides are likely to have novel and in the case of relaxin-1, which is still under positive selection in humans and the great apes, possibly still evolving functions.
Similar(54)
This high degree of conservation suggests a fundamental and slowly evolving function in vertebrates.
There are additional suggestions of evolving function in the PRR7 lineage.
Our control of the stuff of life is such that we can now eschew DNA's evolved functions altogether.
There needs to be more research to determine whether it has an evolved function, or possibly several evolved functions (or possibly no function, as some argue).
Comparisons with published structures from other bacterial systems reveal that secretins have regions of local structural flexibility, probably reflecting their evolved functions in protein secretion and needle assembly.
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