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Given that humans probably evolved close to sea level, the human cachectic response to high altitude, at least in lowland natives, is unlikely to have resulted from altitude-related selection pressure.
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But fossil evidence, the gold standard for natural history, suggests that lemurs actually evolved closer to 20 million years ago.
For instance, one can simply eliminate the fast-evolving taxa, and replace them by slow-evolving close relatives.
So they've been evolving close to the market you're designing for, to understand the end consumer.
Eight cases of large-scale gravitational movements (with evidence of rock-slide type displacements) evolving close to Quaternary faults have been analysed in the Central Apennines.
Except for initial extinctions, the observed extinctions are mostly due to deterministic forces of susceptibles depletion and not to random fluctuations of trajectories evolving close to one individual (low variances in the box plots of figure 5).
We also detect ancient traces of selection in DNA sequences of the HLA-DPB1 locus, which was assumed to evolve close to neutral conditions on the basis of allelic frequencies distributions.
The feedback system in those meetings was ensured to evolve close interaction between field workers and supervisors.
For all these genes, there is a clear peak and a substantial proportion of sites evolving close to neutrality.
Though the definition of the "sufficient" level of adherence is still evolving, close adherence to ART remains important to achieving viral suppression, reduced risk of disease progression and better survival [ 4- 6].
As a result, it has been proposed that RNA viruses evolve close to the error threshold [ 15] and that drift in the consensus sequence is not necessarily accompanied by changes in viability, due to degeneration [ 16].
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