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Our results suggest that mutation rates can evolve markedly over short evolutionary timescales and suggest the possibility of mapping mutational modifiers.
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A distinct lesbian style, Ms. Steele said, has evolved markedly through the last century.
His work has evolved markedly but has always kept its course — Zen-derived, slow-paced, quiet and dignified.
She said the discourse had evolved markedly between the third donor conference in Kuwait in March 2015 and the donor meeting held in London this month.
However, systemic therapy for metastatic renal cell carcinoma has evolved markedly over the past decade, with targeted therapies representing the standard of care in the front-line setting.
Methods of collection, preparation, and transfusion of platelet components have evolved markedly since the introduction of modern platelet transfusion therapy three decades ago.
Entrepreneurship research has evolved markedly over the past three decades and has grown from an embryonic and fragmented state (Shane and Venkataraman 2000; Busenitz et al. 2003; Zahra 2005; Schildt et al. 2006), with its legitimacy being questioned (Low and MacMillan, 1988), to a maturing field of study (Meyer et al. 2012; Busenitz et al. 2014; van Burg and Romme 2014).
Drug-based treatment of rheumatoid arthritis (RA) has evolved markedly over the past 2 decades.
Psychosocial approaches to treating AUDs have evolved markedly over the past few decades.
System-level interventions have evolved markedly since 2000; the lack of association of programs with outcomes in 2000 may not generalize to the current context.
A main pattern of evolutionary change noticed by Riedl was that different characters evolve at markedly different rates and that traits associated with body plans evolve particularly slowly (Wagner and Laubichler 2004).
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