Sentence examples for evolutionary selectivity from inspiring English sources

If the SLiM is under the same evolutionary selectivity as the full-length protein, then the probability that the SLiM is conserved between the two species should be: P 1(i) = p(i) n The probability that the SLiM is unconserved should be: P 2(i) = 1- P 1(i) = 1-p(i) n The SLiM is considered unconserved if any gap occurs within its sequence alignments.

These cavities may have undergone evolutionary selection to adapt GPCRs to particular signalling niches, and may provide targeting opportunities to enhance drug selectivity.

From an evolutionary perspective, this selectivity makes sense: Poisonous food is a much bigger problem than shocks in the wild.

A high degree of specificity among human SH2 domains, combined with cell-specific expression is consistent with the notion that evolutionary pressures drive selectivity of protein-ligand interactions.

From an evolutionary perspective, the low selectivity may be advantageous since mutations would allow rapid adaptation to changes in compartmentation of metabolism.

Some of the key evolutionary transitions in ligand selectivity for NR1I receptors are indicated in the phylogeny shown in Figure 4.

Consistent with fine-tuning of PSAC solute selectivity by evolutionary pressures, this level of Na+ exclusion is sufficient to prevent osmotic lysis of infected cells before completion of the parasite's intracellular cycle [ 17].

Although selection from size-selective fishing gear has been quantified in earlier studies (e.g. Law and Rowell 1993), this is to our knowledge the first paper to systematically investigate the potential evolutionary consequences of size-selectivity harvesting on fish life histories.

We focus on the evolutionary effects of size-selective fishing because regulation of gear selectivity may be an efficient management tool.

The evolutionary basis for this substrate selectivity is discussed with respect to the homologous dienelactone hydrolase.

As global aquatic environments continue to be exploited by commercial, recreational, and subsistence fisheries, it is important to understand fisheries selectivity and the evolutionary consequences of angling.