Thus, the evolutionary retention of these domains suggests critical functions which may or may not influence its role as a histone deacetylase.
We investigate the evolutionary retention of a fragmented pathway for the essential nutrient pantothenate (vitamin B5) in the pea aphid, Acyrthosiphon pisum endosymbiosis with Buchnera aphidicola.
The evolutionary retention of fragmented metabolic pathways in the gene-poor genomes of endosymbionts suggests that they are functional.
In the absence of a clear rationale to justify the evolutionary retention of a death only pathway, we hypothesize that yca1 also influences non-apoptotic events.
However, the evolutionary retention of duplicate genes is also relatively common 91.
The evolutionary retention of variable regions as described here is most likely an indication of their functional significance.
Our operational definition of a Core set of genes was meant to reflect the evolutionary retention of a set of common genes in all E. coli strains.
Due to different mutation rates and repair efficiencies, differential methylation might result in differences in the evolutionary retention of CpGs in paternally and maternally expressed genes.
In principle, any noncoding region of the genome whose primary DNA sequence is important functionally would be similarly constrained as a target for the evolutionary retention of de novo, sequence-dependent hotspots.
One plausible explanation for the evolutionary retention of two or more FFRPs with similar target genes is that they might contribute to fitness in different contexts or respond to different effector molecules.
