The evolutionary record of the genus Orcinus is scanty.
Here we have shown that the combination of naturally occurring somatic mutations coupled with the unique anatomy of the intestinal crypt provides a platform from which the evolutionary record of the human intestinal stem cell compartment can be inferred.
When possible, the structural conservation of predicted pockets was measured considering the evolutionary record of the protein family, given that conserved pockets may have a relevant biological role [ 12].
Because no RSSs or unique spacers were observed in SSSs part of spacers array in this research, we supposed that the latter situation did not occur in Y. pestis and assumed that the information preserved in spacers arrays would show the directionally evolutionary record of this species.
For these reasons, the evolutionary record of Bovini provides an exemplary resource for studies on evolutionary patterns and processes.
The sequence alignment contains the long-term evolutionary record of a protein family and SCA assumes that functionally relevant coupling between amino acids should drive co-evolution of those residues.
Therefore, complementary, inexpensive and scalable approaches search for functional sites and residues by analyzing the vast evolutionary record of protein sequences computationally (Aloy et al., 2001; Buslje et al., 2010; Casari et al., 1995; Engelen et al., 2009; Glaser et al., 2003; Halabi et al., 2009; Innis, 2007; Pupko et al., 2002; Pazos et al., 2006; Valdar, 2002).
In search of an evolutionary record of sorts, Mary F. Corey, an historian affiliated with the University of California at Los Angeles, scrutinizes The New Yorker's output during the postwar years, when the magazine necessarily immersed itself in the era's defining issues: McCarthyism and the Cold War, the emerging civil rights consciousness and the increasing presence of women in public life.
In a real-world scenario, where we might not know this a priori, there may be conflicting constraints in the evolutionary record corresponding to the different positions of the flexible portion of ε subunit.
After all, they argue, the evolutionary record shows plenty of lineages moving from complex structures to simpler ones, to say nothing of extinction — both of which throw cold water on the notion of teleology.
The first debate regards the timing of the emergence of bipedalism in the evolutionary record.
